购物车
- 全部删除
- 您的购物车当前为空
Anti-M-CSF/CSF1 Antibody (7G750) 是一种 Rabbit 抗体,靶向 M-CSF/CSF1。Anti-M-CSF/CSF1 Antibody (7G750) 可用于 ELISA。
Anti-M-CSF/CSF1 Antibody (7G750) 是一种 Rabbit 抗体,靶向 M-CSF/CSF1。Anti-M-CSF/CSF1 Antibody (7G750) 可用于 ELISA。
产品描述 | Anti-M-CSF/CSF1 Antibody (7G750) is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (7G750) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7G750 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse M-CSF / CSF-1 (TMPY-03537; P07141-1; Met1-Glu262). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse M-CSF / CSF-1 protein (TMPY-03537) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容