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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody

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货号 TMAB-11206

Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-RACGAP1 (Ser387)。Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody 可用于 WB。

Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody

Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11206

Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-RACGAP1 (Ser387)。Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RACGAP1 (Ser387). Anti-Phospho-RACGAP1 (Ser387) Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Cow)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle.
组织特异性Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human RACGAP1 around the phosphorylation site of Ser387
抗原种属
Human
基因名称
RACGAP1
基因ID
29127
蛋白名称
Rac GTPase-activating protein 1
Uniprot ID
Q9H0H5
功能
Component of the centralspindlin complex that serves asa microtubule-dependent and Rho-mediated signaling required for themyosin contractile ring formation during the cell cyclecytokinesis. Plays key roles in controlling cell growth anddifferentiation of hematopoietic cells through mechanisms otherthan regulating Rac GTPase activity. Also involved in theregulation of growth-related processes in adipocytes and myoblasts.May be involved in regulating spermatogenesis and in the RACGAP1pathway in neuronal proliferation. Shows strong GAP (GTPaseactivation) activity towards CDC42 and RAC1 and less towards RHOA.Essential for the early stages of embryogenesis. May play a role inregulating cortical activity through RHOA during cytokinesis. Mayparticipate in the regulation of sulfate transport in male germcells.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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