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Anti-MICB Monoclonal Antibody

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产品编号 TMAZ-0189

别名 MHC class I polypeptide-related sequence B

Anti-MICB Monoclonal Antibody is a humanized rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody can be used in ELISA, FCM, IF. 可用于 ELISA,FCM,IF。

Anti-MICB Monoclonal Antibody

Anti-MICB Monoclonal Antibody

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产品编号 TMAZ-0189 别名 MHC class I polypeptide-related sequence B

Anti-MICB Monoclonal Antibody is a humanized rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody can be used in ELISA, FCM, IF. 可用于 ELISA,FCM,IF。

规格价格库存数量
25 μg
¥ 802
7日内发货
50 μg
¥ 962
7日内发货
100 μg
¥ 1,346
7日内发货
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产品介绍

生物活性
产品描述
Anti-MICB Monoclonal Antibody is a humanized rabbit antibody targeting MICB. Anti-MICB Monoclonal Antibody can be used in ELISA,FCM,IF.
别名MHC class I polypeptide-related sequence B
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of MICB overexpressed 326F cells with TMAZ-0189, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用ELISAFCMIF
推荐剂量
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MICB protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8+ alphabeta T-cells (PubMed: 11777960, PubMed: 11491531). Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin
可提供抗体种类
2
抗原信息
免疫原
MICB
抗原种属
Human
基因ID
4277
Uniprot ID
Q29980
研究领域
Drug Target
化学信息
分子量150 kDa
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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