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顶部生物活性储存和溶解信息计算器

Anti-Ano1 Antibody (1J659)

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Anti-Ano1 Antibody (1J659)
产品编号 TMAY-00516
别名 TMEM16A, TAOS2, ORAOV2, MYMY7, INDMS, FLJ10261, DOG1, ANO1

Anti-Ano1 Antibody (1J659) 是一种 Rabbit 抗体，靶向 Ano1。Anti-Ano1 Antibody (1J659) 可用于 WB。

Anti-Ano1 Antibody (1J659)

Anti-Ano1 Antibody (1J659)

Rating icon 还可以
Anti-Ano1 Antibody (1J659)
产品编号 TMAY-00516 别名 TMEM16A, TAOS2, ORAOV2, MYMY7, INDMS, FLJ10261, DOG1, ANO1

Anti-Ano1 Antibody (1J659) 是一种 Rabbit 抗体，靶向 Ano1。Anti-Ano1 Antibody (1J659) 可用于 WB。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-Ano1 Antibody (1J659) is a Rabbit antibody targeting Ano1. Anti-Ano1 Antibody (1J659) can be used in WB.
别名TMEM16A, TAOS2, ORAOV2, MYMY7, INDMS, FLJ10261, DOG1, ANO1
Ig Type
Rabbit IgG
克隆号
1J659
交叉反应
Human
验证活性
Anti-ANO1 rabbit monoclonal antibody at 1:500 dilution.
-Lane A: A549 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.
-Developed using the ECL technique.
-Performed under reducing conditions.
-Predicted band size:114 kDa.
-Observed band size:114 kDa
应用
WB
推荐剂量
WB: 1:500-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the C-terminus of the Human Ano1.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Anoctamin1 (Ano1 and TMEM16A) is a calcium-activated chloride channel specifically expressed in the interstitial cells of Cajal (ICC) of the gastrointestinal tract muscularis propria. Ano1 is a recently discovered Ca(2+)-activated Cl(-) channel expressed on interstitial cells of Cajal (ICC) that has been implicated in slow-wave activity in the gut. However, Ano1 is expressed on all classes of ICC, even those that do not contribute to generation of the slow wave, suggesting that Ano1 may have an alternate function in these cells. Ano1 is also highly expressed in gastrointestinal stromal tumors. Mice lacking Ano1 had fewer proliferating ICC in whole mount preparations and in culture, raising the possibility that Ano1 is involved in proliferation. Ano1 had less phosphorylated retinoblastoma protein compared with controls. Ano1 regulates proliferation at the G(1)/S transition of the cell cycle and may play a role in tumorigenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: C-terminus of the Human Ano1
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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