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Anti-NAALADL1 Antibody (6J529)
还可以产品编号 TMAY-01698
Anti-NAALADL1 Antibody (6J529) 是一种 Mouse 抗体，靶向 NAALADL1。Anti-NAALADL1 Antibody (6J529) 可用于 ELISA。
Anti-NAALADL1 Antibody (6J529)
Anti-NAALADL1 Antibody (6J529)
还可以产品编号 TMAY-01698
Anti-NAALADL1 Antibody (6J529) 是一种 Mouse 抗体，靶向 NAALADL1。Anti-NAALADL1 Antibody (6J529) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-NAALADL1 Antibody (6J529) is a Mouse antibody targeting NAALADL1. Anti-NAALADL1 Antibody (6J529) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 6J529 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NAALADL1 (rh NAALADL1; TMPY-01215; NP_005459.2; Pro 29-Leu 740). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidyl-peptidase, is a Single-pass type II membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus, and ventral striatum. NAALADase L is a chloride-activated, membrane-bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human NAALADL1 protein (TMPY-01215) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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