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Anti-LPA1 Antibody (5L652) 是一种 Rabbit 抗体,靶向 LPA1。Anti-LPA1 Antibody (5L652) 可用于 IHC-P,IHC-Fr,IF。
Anti-LPA1 Antibody (5L652) 是一种 Rabbit 抗体,靶向 LPA1。Anti-LPA1 Antibody (5L652) 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-LPA1 Antibody (5L652) is a Rabbit antibody targeting LPA1. Anti-LPA1 Antibody (5L652) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 5L652 |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell surface. Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles. |
| 组织特异性 | Expressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, and kidney. Little or no expression in liver, lung, thymus, or peripheral blood leukocytes. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G12/G13, and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels. |
| 免疫原 | A synthesized peptide: human LPA receptor 1 |
| 抗原种属 | Human |
| 基因名称 | LPAR1 |
| 基因ID | |
| 蛋白名称 | Lysophosphatidic acid receptor 1 |
| Uniprot ID | |
| 功能 | Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation. |
| 分子量 | Theoretical: 41 kDa. Actual: 39 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |