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顶部生物活性储存和溶解信息计算器

Anti-DEP-1 Antibody (1M971)

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产品编号 TMAY-02515

别名 SCC1, R-PTP-ETA, protein tyrosine phosphatase, receptor type, J, HPTPeta, DEP1, CD148

Anti-DEP-1 Antibody (1M971) 是一种 Mouse 抗体，靶向 DEP-1。Anti-DEP-1 Antibody (1M971) 可用于 ELISA。

Anti-DEP-1 Antibody (1M971)

Anti-DEP-1 Antibody (1M971)

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Rating icon 还可以
产品编号 TMAY-02515 别名 SCC1, R-PTP-ETA, protein tyrosine phosphatase, receptor type, J, HPTPeta, DEP1, CD148

Anti-DEP-1 Antibody (1M971) 是一种 Mouse 抗体，靶向 DEP-1。Anti-DEP-1 Antibody (1M971) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-DEP-1 Antibody (1M971) is a Mouse antibody targeting DEP-1. Anti-DEP-1 Antibody (1M971) can be used in ELISA.
别名SCC1, R-PTP-ETA, protein tyrosine phosphatase, receptor type, J, HPTPeta, DEP1, CD148
Ig Type
Mouse IgG1
克隆号
1M971
交叉反应
Human
特异性
Human DEP-1
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DEP1 / PTPRJ (rh DEP1 / PTPRJ; TMPY-02763; Q12913; Arg997-Ala1337). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. DEP1 / PTPRJ possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. DEP1 / PTPRJ is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. In stable MCF-7 cell lines, induction of DEP-1 expression inhibited breast cancer cell growth by 5-10-fold. These data describe PTPs expressed and regulated in breast cancer cell lines during differentiation and identify one PTP, DEP-1, that inhibits the growth of breast cancer cells in vitro.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human DEP1 / PTPRJ Protein (TMPY-02763)
抗原种属
Human
研究领域
Phosphatases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

SCC-1SCC 1DEP-1DEP 1CD-148CD 148

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