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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-UNC5B Polyclonal Antibody

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货号 TMAB-01935

别名 UNC5H2, unc-5 homolog B (C. elegans), p53RDL1

Anti-UNC5B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 UNC5B。Anti-UNC5B Polyclonal Antibody 可用于 WB。

Anti-UNC5B Polyclonal Antibody

Anti-UNC5B Polyclonal Antibody

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货号 TMAB-01935 别名 UNC5H2, unc-5 homolog B (C. elegans), p53RDL1

Anti-UNC5B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 UNC5B。Anti-UNC5B Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-UNC5B Polyclonal Antibody is a Rabbit antibody targeting UNC5B. Anti-UNC5B Polyclonal Antibody can be used in WB.
别名UNC5H2, unc-5 homolog B (C. elegans), p53RDL1
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Horse,Rabbit)
验证活性
25 μg total protein per Lane of various lysates probed with UNC5B polyclonal antibody, unconjugated (TMAB-01935) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein. Note=Associated with lipid raft.
组织特异性Highly expressed in brain. Also expressed at lower level in developing lung, cartilage, kidney and hematopoietic and immune tissues.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human UNC5B
抗原种属
Human
基因名称
UNC5B
基因ID
219699
蛋白名称
Netrin receptor UNC5B
Uniprot ID
Q8IZJ1
研究领域
Endothelium,Axonal Guidance Proteins,Neural Signal Transduction
功能
FunctionReceptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity.
化学信息
分子量Theoretical: 101 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

unc-5 homolog BC. elegans
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