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顶部生物活性储存和溶解信息计算器

Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody

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产品编号 TMAC-01995

别名 p-HNRNPK (Ser216), p-HNRNPK (S216), HNRNPK (p-Ser216), HNRNPK (p-S216)

Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-HNRNPK (Ser216)。Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody 可用于 WB。

Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody

Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody

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Rating icon 还可以
产品编号 TMAC-01995 别名 p-HNRNPK (Ser216), p-HNRNPK (S216), HNRNPK (p-Ser216), HNRNPK (p-S216)

Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-HNRNPK (Ser216)。Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HNRNPK (Ser216). Anti-Phospho-HNRNPK (Ser216) Polyclonal Antibody can be used in WB.
别名p-HNRNPK (Ser216), p-HNRNPK (S216), HNRNPK (p-Ser216), HNRNPK (p-S216)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from JurKat cells, using hnRNP K (Phospho-Ser216) antibody TMAC-01995. The lane on the right is treated with the synthesized peptide.
verifiedActivity
应用WB
推荐剂量
WB: 1:500-3000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction By similarity. As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 216 (S-E-S(p)-P-I) derived from Human hnRNP K
抗原种属
human
Uniprot ID
P61978
化学信息
分子量Actual: 55 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pHNRNPK (Ser216)pHNRNPK (S216)HNRNPK (pSer216)HNRNPK (pS216)HNRNPK (phospho-Ser216)HNRNPK (phospho-S216)

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4个月前
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