规格

价格

库存

数量

2 mg

¥ 176

现货

5 mg

待询

现货

10 mg

待询

现货

生物活性

产品描述	Amifostine thiol (WR-1065) is a radioprotectant that protects DNA from fast neutron-induced strand breaks.Amifostine thiol ameliorates (P<0.001) 6-OHDA-induced stiffness in a dose-dependent manner and activates p53 through a JNK-dependent signaling pathway.
体外活性	4 mM Amifostine thiol 对 X 射线辐照 30 min 诱导的基因组不稳定性具有一定保护作用，同时也能保护 RKO36 细胞免受电离辐射引起的染色体损伤和死亡[1]。
别名	氨磷汀硫化物, WR-1065

化学信息

分子量	134.24
分子式	C₅H₁₄N₂S
CAS No.	31098-42-7
Smiles	NCCCNCCS
颜色	White
物理性状	Solid

储存&溶解度

存储

keep away from direct sunlight,store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 80 mg/mL (595.95 mM), Sonication is recommended.

DMSO: 200 mg/mL (1489.87 mM), Sonication is recommended.

溶液配制表

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	7.4493 mL	37.2467 mL	74.4934 mL	372.4672 mL
5 mM	1.4899 mL	7.4493 mL	14.8987 mL	74.4934 mL
10 mM	0.7449 mL	3.7247 mL	7.4493 mL	37.2467 mL
20 mM	0.3725 mL	1.8623 mL	3.7247 mL	18.6234 mL
50 mM	0.1490 mL	0.7449 mL	1.4899 mL	7.4493 mL
100 mM	0.0745 mL	0.3725 mL	0.7449 mL	3.7247 mL