LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, His)

LILRB1, also known as CD85j and ILT2, is a transmembrane glycoprotein in the LILR immunoregulatory protein family. LILRB1 is expressed on NK cells that have expanded in response to acute HCMV infection. LILRB1 exhibits considerable diversity in the population, and polymorphisms in the LILRB1 gene have been associated with susceptibility to rheumatoid arthritis and weakly associated with HCMV disease in a subset of patients with HIV. The regulation of phagocytosis by macrophages is an additional key role of LILRB1 signaling. LILRB1 recognizes a wide variety of HLA haplotypes due to its interaction with the invariant β2M subunit of MHC class I, which suggests that this signaling axis is relevant across diverse patient populations.

规格	价格/CNY		数量
10 μg	￥ 380	5日内发货
50 μg	￥ 1,170	5日内发货
500 μg	￥ 9,490	5日内发货
1 mg	￥ 14,200	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 380

5日内发货

50 μg

￥ 1,170

5日内发货

500 μg

￥ 9,490

5日内发货

1 mg

￥ 14,200

5日内发货

产品描述

种属	Rhesus
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	F7H3G7
别名	CD85j, ILT2, LILRB1
氨基酸序列	Ser17-His456
蛋白构建	Ser17-His456
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	60-85 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	LILRB1, also known as CD85j and ILT2, is a transmembrane glycoprotein in the LILR immunoregulatory protein family. LILRB1 is expressed on NK cells that have expanded in response to acute HCMV infection. LILRB1 exhibits considerable diversity in the population, and polymorphisms in the LILRB1 gene have been associated with susceptibility to rheumatoid arthritis and weakly associated with HCMV disease in a subset of patients with HIV. The regulation of phagocytosis by macrophages is an additional key role of LILRB1 signaling. LILRB1 recognizes a wide variety of HLA haplotypes due to its interaction with the invariant β2M subunit of MHC class I, which suggests that this signaling axis is relevant across diverse patient populations.

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LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, His)

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