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Anti-PDGFRB Antibody (6N196)
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产品编号 TMAC-03114
别名 PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B
Anti-PDGFRB Antibody (6N196) 是一种 Rabbit 抗体，靶向 PDGFRB。Anti-PDGFRB Antibody (6N196) 可用于 WB,IHC,IP。
Anti-PDGFRB Antibody (6N196)
Anti-PDGFRB Antibody (6N196)
还可以产品编号 TMAC-03114 别名 PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B
Anti-PDGFRB Antibody (6N196) 是一种 Rabbit 抗体，靶向 PDGFRB。Anti-PDGFRB Antibody (6N196) 可用于 WB,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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抗原信息
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| 产品描述 | Anti-PDGFRB Antibody (6N196) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (6N196) can be used in WB,IHC,IP. |
| 别名 | PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of PDGF Receptor beta on NIH/3T3 cell lysates using anti-PDGF Receptor beta antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-PDGF Receptor beta antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-PDGF Receptor beta antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-PDGF Receptor beta antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PDGF Receptor beta antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Platelet-derived growth factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PGDF-AA, PDGF-AB and PDGF-BB. These three isoforms bind with different affinities to two receptor types, PDGFR-α and ?Cβ, which are endowed with protein tyrosine kinase domains. PDGFR-α can bind to both A and B subunits of PDGF, while PDGFR-β can only bind the B subunit. Ligand binding promotes either homo- or heterodimerization of the PDGF receptors in a specific manner. PDGF-AA induces the dimerization of two α receptors, PDGF-AB induces dimerization of αα and αβ and PDGF-BB induces the formation of three types of dimers, αα, αβ and ββ. Translocation of the PDGFR-?? gene with the Tel gene is linked to chronic myelomonocytic leukemia (CMML), a myelodysplastic syndrome, and demonstrates the oncogenic potential of the PDGF receptors. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 170 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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