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顶部生物活性储存和溶解信息计算器

Anti-PDGFRB Antibody (6N196)

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产品编号 TMAC-03114

别名 PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B

Anti-PDGFRB Antibody (6N196) 是一种 Rabbit 抗体，靶向 PDGFRB。Anti-PDGFRB Antibody (6N196) 可用于 IHC,IP,WB。

Anti-PDGFRB Antibody (6N196)

Anti-PDGFRB Antibody (6N196)

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产品编号 TMAC-03114 别名 PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B

Anti-PDGFRB Antibody (6N196) 是一种 Rabbit 抗体，靶向 PDGFRB。Anti-PDGFRB Antibody (6N196) 可用于 IHC,IP,WB。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-PDGFRB Antibody (6N196) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (6N196) can be used in IHC,IP,WB.
别名PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B
Ig Type
IgG
克隆号
6N196
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PDGF Receptor beta on NIH/3T3 cell lysates using anti-PDGF Receptor beta antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-PDGF Receptor beta antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-PDGF Receptor beta antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-PDGF Receptor beta antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PDGF Receptor beta antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用IHCIPWB
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Platelet-derived growth factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PGDF-AA, PDGF-AB and PDGF-BB. These three isoforms bind with different affinities to two receptor types, PDGFR-α and ?Cβ, which are endowed with protein tyrosine kinase domains. PDGFR-α can bind to both A and B subunits of PDGF, while PDGFR-β can only bind the B subunit. Ligand binding promotes either homo- or heterodimerization of the PDGF receptors in a specific manner. PDGF-AA induces the dimerization of two α receptors, PDGF-AB induces dimerization of αα and αβ and PDGF-BB induces the formation of three types of dimers, αα, αβ and ββ. Translocation of the PDGFR-?? gene with the Tel gene is linked to chronic myelomonocytic leukemia (CMML), a myelodysplastic syndrome, and demonstrates the oncogenic potential of the PDGF receptors.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P09619
化学信息
分子量Theoretical: 170 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

PDGFR-betaPDGFR-bPDGFR2PDGFR-1PDGFR 2PDGFR 1PDGF R bJTK-12JTK 12

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