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顶部生物活性储存和溶解信息计算器

Anti-FTO Polyclonal Antibody

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货号 TMAB-00719

Anti-FTO Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FTO。Anti-FTO Polyclonal Antibody 可用于 WB。

Anti-FTO Polyclonal Antibody

Anti-FTO Polyclonal Antibody

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货号 TMAB-00719

Anti-FTO Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FTO。Anti-FTO Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-FTO Polyclonal Antibody is a Rabbit antibody targeting FTO. Anti-FTO Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat
验证活性
Sample:
Lane 1: Mouse Adrenal gland tissue lysates
Lane 2: Rat Adrenal gland tissue lysates
Lane 3: Human SH-SY5Y cell lysates
Lane 4: Human HeLa cell lysates
Lane 5: Human U87MG cell lysates
Lane 6: Human MOLT4 cell lysates
Primary: Anti-FTO (TMAB-00719) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kDa
Observed band size: 60 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Protein fatso
抗原种属
Human
基因名称
FTO
基因ID
79068
蛋白名称
alpha-ketoglutarate-dependent dioxygenase FTO
Uniprot ID
Q9C0B1
研究领域
Diabetes associated,Lipid transport,Lipoprotein metabolism,Lipoprotein metabolism,Cancer,Diabetes,Heart disease,Metabolic disorders,Obesity,Metabolism
功能
Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
化学信息
分子量Theoretical: 58 kDa. Actual: 58 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

α-ketoglutarate-dependent dioxygenase FTOU6 small nuclear RNA N(6)-methyladenosine-demethylase FTOU6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTOtRNA N1-methyl adenine demethylase FTOmRNA N(6)-methyladenosine demethylase FTOmRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (m6A(m)-demethylase FTO)m6A(m-demethylase FTO)KIAA1752KIAA 1752FTOFat mass and obesity-associated proteinAlpha-ketoglutarate-dependent dioxygenase FTOa-ketoglutarate-dependent dioxygenase FTO

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