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Anti-CTCF Antibody (5J799) 是一种 Rabbit 抗体,靶向 CTCF。Anti-CTCF Antibody (5J799) 可用于 WB,ICC/IF,IHC,IP。
Anti-CTCF Antibody (5J799) 是一种 Rabbit 抗体,靶向 CTCF。Anti-CTCF Antibody (5J799) 可用于 WB,ICC/IF,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-CTCF Antibody (5J799) is a Rabbit antibody targeting CTCF. Anti-CTCF Antibody (5J799) can be used in WB,ICC/IF,IHC,IP. |
别名 | Transcriptional Repressor CTCF, CTCFL Paralog, CTCF, CCCTC-Binding Factor, 11-Zinc Finger Protein |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat,zebrafish |
验证活性 | 1. Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-CTCF antibody. 2. Mouse kidney was stained with anti-CTCF rabbit antibody. 3. Rat kidney was stained with anti-CTCF rabbit antibody. 4. Immunofluorescence analysis of HEK293. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:100-500; IP: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | CTCF belongs to the zinc finger transcription factor family, and it recognizes unusually long and remarkably divergent DNA target sequences to influence expression of many various genes. The DNA-binding domain of CTCF is composed of 11 Zn fingers including 10 that are of C2H2 class, and 1 that is of C2HC class, and they are highly conserved between vertebrate species. CTCF functions as a repressor of the c-myc gene and as a regulator of lysozyme gene expression. In addition, CTCF associates with the essential activator domain in the promotor region of the amyloid beta-protein precursor (APP) gene to activate transcription of APP. Expression of CTCF up-regulates APP expression and thereby, enhances synapse formations between primary neurons during development. CTCF is ubiquitously expressed and localized to the nucleus. During terminal differentiation, CTCF is negatively regulated by differential phosphorylation and also by decreases in CTCF mRNA and protein expression. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 140/83 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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