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顶部产品介绍抗原信息储存和溶解信息计算器

Anti-Laminin B1 Antibody (8P706)

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货号 TMAB-08208

Anti-Laminin B1 Antibody (8P706) 是一种 Rabbit 抗体，靶向 Laminin B1。Anti-Laminin B1 Antibody (8P706) 可用于 FCM,WB。

Anti-Laminin B1 Antibody (8P706)

Anti-Laminin B1 Antibody (8P706)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08208

Anti-Laminin B1 Antibody (8P706) 是一种 Rabbit 抗体，靶向 Laminin B1。Anti-Laminin B1 Antibody (8P706) 可用于 FCM,WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

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产品描述
Anti-Laminin B1 Antibody (8P706) is a Rabbit antibody targeting Laminin B1. Anti-Laminin B1 Antibody (8P706) can be used in FCM,WB.
Ig Type
IgG
克隆号
8P706
反应种属
Human,Mouse,Rat
应用FCMWB
推荐剂量
FCM: 1:50-100; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位reted, extracellular space, extracellular matrix, basement membrane. Note: Major component.
组织特异性Expressed in tibial nerve and 196 other tissues
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis. [provided by RefSeq, Aug 2011]
抗原信息
免疫原
A synthesized peptide: human Laminin beta 1
基因名称
LAMB1
基因ID
3912
蛋白名称
Laminin subunit beta-1
功能
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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