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IL-13 Protein, Human, Recombinant (E. coli)

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产品编号 TMPY-01993U

IL-13 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is AAK53823.

IL-13 Protein, Human, Recombinant (E. coli)

一键复制产品信息

产品编号 TMPY-01993U

IL-13 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is AAK53823.

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产品信息

生物活性	Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is typically 0.5-3 ng/mL. (QC Test) Immobilized Human IL-13, No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-13Ra2, His Tag with the EC50 of 3.6 ng/ml determined by ELISA. (QC Test) Loaded Human IL-13Ra2, His Tag on Anti-His-Biosensor can bind Human IL-13, No Tag with an affinity constant of 0.63 nM as determined in BLI assay (Gator® Prime).
产品描述	IL-13 Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is AAK53823.
种属	Human
表达系统	E. coli
蛋白编号	AAK53823
别名	白细胞介素,P600,interleukin 13,IL-13,ALRH
蛋白构建	Gly21-Asn132
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
分子量	12.34 kDa (Predicted and reducing conditions)
内毒素	< 0.1 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).