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Anti-Aminopeptidase N/CD13 Antibody (3R860)
还可以产品编号 TMAY-00183
Anti-Aminopeptidase N/CD13 Antibody (3R860) 是一种 Rabbit 抗体，靶向 Aminopeptidase N/CD13。Anti-Aminopeptidase N/CD13 Antibody (3R860) 可用于 ICC/IF。
Anti-Aminopeptidase N/CD13 Antibody (3R860)
Anti-Aminopeptidase N/CD13 Antibody (3R860)
还可以产品编号 TMAY-00183
Anti-Aminopeptidase N/CD13 Antibody (3R860) 是一种 Rabbit 抗体，靶向 Aminopeptidase N/CD13。Anti-Aminopeptidase N/CD13 Antibody (3R860) 可用于 ICC/IF。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Aminopeptidase N/CD13 Antibody (3R860) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (3R860) can be used in ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3R860 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of Human CD13 in MSC cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human CD13 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD13 / ANPEP (rh CD13 / ANPEP; TMPY-00665; NP_001141.2; Lys69-Lys967,603Met/Ile). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 family. CD13 plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases and is involved in the metabolism of regulatory peptides by diverse cell types. CD13/APN is a potent regulator of angiogenesis which is essential for tumor invasion and metastasis, and its transcription in activated endothelial cells is induced by angiogenic growth factors via the RAS/MAPK pathway. In addition, this enzyme has been shown to participate in antigen processing and presentation, and accordingly, defects in this gene appear to be a cause of various types of leukemia or lymphoma and carcinomas. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CD13 / ANPEP Protein (TMPY-00665) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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