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IL-12B Protein, Mesocricetus auratus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.8 kDa and the accession number is Q8CJE6.

| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 5 μg | ¥ 555  | 20日内发货 | |
| 10 μg | ¥ 890  | 20日内发货 | |
| 20 μg | ¥ 1,510  | 20日内发货 | |
| 50 μg | ¥ 2,270  | 20日内发货 | |
| 100 μg | ¥ 3,120  | 20日内发货 | |
| 200 μg | ¥ 4,790  | 20日内发货 | |
| 500 μg | ¥ 8,580  | 20日内发货 | |
| 1 mg | ¥ 13,300  | 20日内发货 | 
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.  | 
| 产品描述 | IL-12B Protein, Mesocricetus auratus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.8 kDa and the accession number is Q8CJE6.  | 
| 种属 | Mesocricetus auratus  | 
| 表达系统 | E. coli  | 
| 标签 | N-10xHis, C-Myc | 
| 蛋白编号 | Q8CJE6 | 
| 别名 | Interleukin-12 subunit beta,IL-12B,IL12B,IL-12 subunit p40,Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40)  | 
| 氨基酸序列 | IWELEKDVYVVEVDWSPDAAGERVVLTCDTSEEDDIIWTSDKNSEAVGSGKTLTIQVKEFSNAGQYTCHKGGKTLSHSRLLLHKKENGIWSTDILKDQKDPKNKTFLKCEAANYSGRFTCWWLTAISTDLKFNVKSSSSSSDSRAVTCGAASLSAEKVTVDRKDYQKYSVACQEDITCPTAEETLPIGLVMEAQHKYKYENYSTGFFIRDIIKPDPPKNLQLKPLRGSQMELSWEYPDSWSTPHSYFSLKFHVQVHRKRERKDESQFVDKTSATIRCSKGAEVRVRAQDHYYNSSWSRWVSVPCS  | 
| 蛋白构建 | 23-327 aa  | 
| 蛋白纯度 | > 85% as determined by SDS-PAGE. ![]()  | 
| 分子量 | 39.8 kDa (predicted) | 
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. | 
| 缓冲液 | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. | 
| 复溶方法 | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.  | 
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.  | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| 研究背景 | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.; Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.  |