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Anti-Lamin B Receptor Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Lamin B Receptor。Anti-Lamin B Receptor Polyclonal Antibody 可用于 WB,FCM。
Anti-Lamin B Receptor Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Lamin B Receptor。Anti-Lamin B Receptor Polyclonal Antibody 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Lamin B Receptor Polyclonal Antibody is a Rabbit antibody targeting Lamin B Receptor. Anti-Lamin B Receptor Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Cow,Horse,Rabbit) |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus inner membrane; Multi-pass membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death. |
| 免疫原 | KLH conjugated synthetic peptide: human Lamin B Receptor |
| 抗原种属 | Human |
| 基因名称 | LBR |
| 基因ID | |
| 蛋白名称 | delta(14)-sterol reductase LBR |
| Uniprot ID | |
| 功能 | Anchors the lamina and the heterochromatin to the inner nuclear membrane. |
| 分子量 | Theoretical: 68 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |