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Anti-HECA Polyclonal Antibody

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货号 TMAB-06962

Anti-HECA Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HECA。Anti-HECA Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-HECA Polyclonal Antibody

Anti-HECA Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06962

Anti-HECA Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HECA。Anti-HECA Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-HECA Polyclonal Antibody is a Rabbit antibody targeting HECA. Anti-HECA Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Expressed in all tissues examined. Highest levels are in the spleen, thymus, peripheral blood and heart. Lowest in the kidney and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景HECA, also known as headcase homolog, HDC, HDCL or HHDC, is a 543 amino acid mammalian homolog of the Drosophila headcase protein, a highly basic, cytplasmic peptide that plays a role in mitotic re-entry during adult morphogenesis. Expressed in a variety of tissues with highest expression in thymus, spleen and heart, HECA is thought to play a role in the development of epithelial tube networks in lung tissue and may also be involved in the pathogenesis of lung cancer. The gene encoding HECA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HECA
抗原种属
Human
基因名称
HECA
基因ID
蛋白名称
Headcase protein homolog
Uniprot ID
功能
May play an important role in some human cancers. May bepart of the regulatory mechanism in the development of epithelialtube networks such as the circulatory system and lungs.
化学信息
分子量Theoretical: 59 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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