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PSGL-1/CD162 Protein, Human, Recombinant (His)

PSGL-1/CD162 Protein, Human, Recombinant (His)

产品编号 TMPY-03531
别名: selectin P ligand, PSGL-1, PSGL1, CD162, CLA

PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.

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PSGL-1/CD162 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 现货
200 μg ¥ 6,750 5日内发货
500 μg ¥ 14,280 5日内发货
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产品目录号及名称: PSGL-1/CD162 Protein, Human, Recombinant (His) (TMPY-03531)
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产品描述 PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 Q14242-1
别名 selectin P ligand, PSGL-1, PSGL1, CD162, CLA
蛋白构建 Human SELPLG (Q14242-1) (Met1-Gly295) with a C-terminal polyhistidine tag
蛋白纯度 ≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

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分子量 30.5 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.

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Keywords

PSGL-1/CD162 Protein, Human, Recombinant (His) PSGL 1 selectin P ligand CD 162 CD-162 PSGL-1 PSGL1 CD162 CLA recombinant recombinant-proteins proteins protein

 

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