Anti-DR6 Antibody (2S189)

Name: Anti-DR6 Antibody (2S189)
Brand: TargetMol
SKU: TMAY-00406
Rating: 4.5 (1 reviews)

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产品编号 TMAY-00406

别名 tumor necrosis factor receptor superfamily, member 21

Anti-DR6 Antibody (2S189) 是一种 Rabbit 抗体，靶向 DR6。Anti-DR6 Antibody (2S189) 可用于 ELISA。

Anti-DR6 Antibody (2S189)

还可以

产品编号 TMAY-00406 别名 tumor necrosis factor receptor superfamily, member 21

Anti-DR6 Antibody (2S189) 是一种 Rabbit 抗体，靶向 DR6。Anti-DR6 Antibody (2S189) 可用于 ELISA。

规格	价格	库存	数量
100 μL	¥ 2,279	5日内发货

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产品描述	Anti-DR6 Antibody (2S189) is a Rabbit antibody targeting DR6. Anti-DR6 Antibody (2S189) can be used in ELISA.
别名	tumor necrosis factor receptor superfamily, member 21
Ig Type	Monoclonal Rabbit IgG
克隆号	2S189
交叉反应	Human
应用	ELISA
推荐剂量	ELISA: 1:5000-1:10000
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Human TNFRSF21 (rh TNFRSF21; TMPY-01341; Met 1-Leu 350; NP_055267.1) .
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	TNFRSF21 (death receptor-6, DR6) is an orphan TNF receptor superfamily member and belongs to a subgroup of receptors called death receptors. This type I transmembrane receptor possesses four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is an extensively posttranslationally modified transmembrane protein and that N- and O-glycosylations of amino acids in its extracellular part. DR6 interacts with the adaptor protein TRADD and mediates signal transduction through its death domain, and expression of DR6 in mammalian cells induces activation of both NF-kappaB and JNK and cell apoptosis. DR6 knockout mice have enhanced CD4+ T cell proliferation and Th2 cytokine production, suggested that DR6 serves as an important regulatory molecule in T-helper cell activation, and is involved in inflammation and immune regulation. DR6 is expressed ubiquitously with high expression in lymphoid organs, heart, brain and pancreas. Some tumor cells overexpress DR6, typically in conjunction with elevated anti-apoptosis molecules. DR6 may also be involved in tumor cell survival and immune evasion, which is subject to future investigations.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human DR6 protein (TMPY-01341)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.