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Anti-Clusterin Antibody-FITC (9C938) 是一种 FITC-conjugated Mouse 抗体,靶向 Clusterin。Anti-Clusterin Antibody-FITC (9C938) 可用于 FCM。
Anti-Clusterin Antibody-FITC (9C938) 是一种 FITC-conjugated Mouse 抗体,靶向 Clusterin。Anti-Clusterin Antibody-FITC (9C938) 可用于 FCM。
产品描述 | Anti-Clusterin Antibody-FITC (9C938) is a FITC-conjugated Mouse antibody targeting Clusterin. Anti-Clusterin Antibody-FITC (9C938) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 9C938 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human CLU expression in A549 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC Mouse anti-Human CLU. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Clusterin / Apolipoprotein J / Apo-J (rh Clusterin / Apolipoprotein J / Apo-J; TMPY-01691; NP_001822.2; Met1-Glu501) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others. |
偶联 | FITC |
其他可选修饰符 | Unconjugated/PE |
可提供抗体种类 | 3 |
免疫原 | Recombinant Human Clusterin / Apolipoprotein J / Apo-J protein (TMPY-01691) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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