sST2 Protein, Human, Recombinant

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产品编号 TMPY-07207

sST2 Protein, Human, Recombinant is expressed in E. coli.

sST2 Protein, Human, Recombinant

一键复制产品信息

产品编号 TMPY-07207

sST2 Protein, Human, Recombinant is expressed in E. coli.

规格	价格	库存	数量
250 μg	待询	5日内发货

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产品信息

生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	sST2 Protein, Human, Recombinant is expressed in E. coli.
种属	Human
表达系统	E. coli
别名	T1,ST2V,ST2L,ST2,IL33R,FIT-1,DER4
蛋白纯度	≥ 90% as determined by SDS-PAGE.
分子量	35.82 kDa (predicted)
内毒素	Please contact us for more information.
缓冲液	Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 4 M Urea, 10% Glycerol, pH 7.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
复溶方法	Please refer to the lot-specific COA.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.