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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ENPP1 Antibody (3J87)

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货号 TMAB-05583

Anti-ENPP1 Antibody (3J87) 是一种 Rabbit 抗体，靶向 ENPP1。Anti-ENPP1 Antibody (3J87) 可用于 IHC-P,IHC-Fr,IF。

Anti-ENPP1 Antibody (3J87)

Anti-ENPP1 Antibody (3J87)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05583

Anti-ENPP1 Antibody (3J87) 是一种 Rabbit 抗体，靶向 ENPP1。Anti-ENPP1 Antibody (3J87) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-ENPP1 Antibody (3J87) is a Rabbit antibody targeting ENPP1. Anti-ENPP1 Antibody (3J87) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
3J87
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic
组织特异性Expressed in plasma cells and also in a number of non-lymphoid tissues, including the distal convoluted tubule of the kidney, chondrocytes and epididymis.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景ENPP1 has a broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. It can hydrolyze nucleoside 5' triphosphates such as ATP, GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate. It can also hydrolyze diadenosine polyphosphates and 3',5'-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. The subtilisin-like Prohormone Convertase (PC) family is a group of cellular enzymes that cleave most prohormones and neuropeptide precursors. Numerous other cellular proteins, some viral proteins, and bacterial toxins that are transported by the constitutive secretory pathway are also targeted for maturation by PCs. PC family members share structural similarities, which include a heterogeneous ~10 kDa amino-terminal proregion, a highly conserved ~55 kDa subtilisin-like catalytic domain, and carboxyl-terminal domain that is heterogeneous in length and sequence. These enzymes become catalytically active following proregion cleavage within the appropriate cellular compartment. The subcellular localization of PC family members varies. Immunolocalization studies show that PC1 is found in the perinuclear region as well as the trans-Golgi network, whereas PC2 can be found in the trans-Golgi network as well as diffusely distributed in the peripheral cytoplasm.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ENPP1
抗原种属
Human
基因名称
ENPP1
基因ID
5167
蛋白名称
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Uniprot ID
P22413
功能
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.
化学信息
分子量Theoretical: 100 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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