Name: FGF-21 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-01889
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 373

6-8日内发货

10 μg

¥ 588

6-8日内发货

20 μg

¥ 983

5日内发货

50 μg

¥ 1,950

5日内发货

100 μg

¥ 3,280

5日内发货

200 μg

¥ 5,550

5日内发货

500 μg

¥ 10,800

5日内发货

1 mg

¥ 21,800

5日内发货

生物活性

产品描述	FGF-21 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.2 kDa and the accession number is A0A7U3L5M7.
生物活性	Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.1-1 µg/mL in the presence of 2.5 µg/mL of rmKlotho β.
研究背景	Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.
种属	Human
表达系统	E. coli
标签	N-His
蛋白编号	Q9NSA1
蛋白构建	A DNA sequence encoding the mature form of human FGF21 (NP_061986.1) (His 29-Ser 209) was expressed, with a polyhistide tag at the N-terminus. Predicted N terminal: Met
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 50 mM Tris, 10% glycerol, 0.05% Brij 35, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	成纤维细胞生长因子, UNQ3115 / PRO10196, fibroblast growth factor 21
内毒素	Please contact us for more information.

化学信息

分子量	20.2 kDa (predicted); 23 kDa (reducing conditions)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

FGF-21 Protein, Human, Recombinant (His)

FGF-21 Protein, Human, Recombinant (His)

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