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Anti-MRFAP1L1 Polyclonal Antibody

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货号 TMAB-08990

Anti-MRFAP1L1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MRFAP1L1。Anti-MRFAP1L1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MRFAP1L1 Polyclonal Antibody

Anti-MRFAP1L1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08990

Anti-MRFAP1L1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MRFAP1L1。Anti-MRFAP1L1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-MRFAP1L1 Polyclonal Antibody is a Rabbit antibody targeting MRFAP1L1. Anti-MRFAP1L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane
组织特异性Expressed ubiquitously but at low levels.Shows a strong expression in the erythrocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The members of the mortality factor family include mortality factor 4 (MORF4), MORF4L1 (also known as MRG15) and MORF4-related gene X (MRGX). The human MORF4 gene maps to chromosome 4q33-q34.1. MORF4 induces a senescent-like phenotype in complementation group B immortal cell lines. MORF4 family-associated protein 1 (MRFAP1), also known as GAM14 or PGR1, is a 127 amino acid member of the MORF4 family-associated protein family. Localized to nucleus and cytoplasm, MRFAP1 colocalizes with MORF4L1 to the cell nuclei. Its association with MORF4L1 and Rb1 suggests that MRFAP1 may play a role in transcription regulation. The gene encoding human MRFAP1 maps to chromosome 4p16.1.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MRFAP1L1
抗原种属
Human
基因名称
MRFAP1L1
基因ID
114932
蛋白名称
MORF4 family-associated protein 1-like 1
Uniprot ID
Q96HT8
功能
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX)and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
化学信息
分子量Theoretical: 15 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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