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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GPR120 Polyclonal Antibody

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货号 TMAB-00789

别名 PGR4, PGR 4, Omega-3 fatty acid receptor 1, O3FAR1, O3FA1, MGC119984, HGNC:19345, GT01, GPR129, GPR120, GPR 129, GPR 120, GPCR GPR120, G protein coupled receptor PGR4, G protein coupled receptor PGR 4, G protein coupled receptor GT01, G protein coupled receptor 129, G protein coupled receptor 120

Anti-GPR120 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR120。Anti-GPR120 Polyclonal Antibody 可用于 ELISA,ICC/IF,WB。

Anti-GPR120 Polyclonal Antibody

Anti-GPR120 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00789 别名 PGR4, PGR 4, Omega-3 fatty acid receptor 1, O3FAR1, O3FA1, MGC119984, HGNC:19345, GT01, GPR129, GPR120, GPR 129, GPR 120, GPCR GPR120, G protein coupled receptor PGR4, G protein coupled receptor PGR 4, G protein coupled receptor GT01, G protein coupled receptor 129, G protein coupled receptor 120

Anti-GPR120 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR120。Anti-GPR120 Polyclonal Antibody 可用于 ELISA,ICC/IF,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-GPR120 Polyclonal Antibody is a Rabbit antibody targeting GPR120. Anti-GPR120 Polyclonal Antibody can be used in ELISA,ICC/IF,WB.
别名PGR4, PGR 4, Omega-3 fatty acid receptor 1, O3FAR1, O3FA1, MGC119984, HGNC:19345, GT01, GPR129, GPR120, GPR 129, GPR 120, GPCR GPR120, G protein coupled receptor PGR4, G protein coupled receptor PGR 4, G protein coupled receptor GT01, G protein coupled receptor 129, G protein coupled receptor 120
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Rabbit)
应用ELISAICC/IFWB
推荐剂量
WB: 1:500-2000; ICC/IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Colocalized with ARRB2 following DHA treatment.
组织特异性Abundant expression in the intestinal tract.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human G protein coupled receptor 120
抗原种属
Human
基因名称
FFAR4
基因ID
338557
蛋白名称
Free fatty acid receptor 4
Uniprot ID
Q5NUL3
研究领域
Lipid metabolism,GPCR
功能
Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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