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Anti-GPR120 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPR120。Anti-GPR120 Polyclonal Antibody 可用于 WB,ICC/IF,ELISA。
Anti-GPR120 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPR120。Anti-GPR120 Polyclonal Antibody 可用于 WB,ICC/IF,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,165 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-GPR120 Polyclonal Antibody is a Rabbit antibody targeting GPR120. Anti-GPR120 Polyclonal Antibody can be used in WB,ICC/IF,ELISA. |
Ig Type | IgG |
交叉反应 | Human,Mouse (predicted:Rat,Dog,Pig,Cow,Rabbit) |
应用 | |
推荐剂量 | WB: 1:500-2000; ICC/IF: 1:100-500; ELISA: 1:5000-10000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cell membrane. Colocalized with ARRB2 following DHA treatment. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes. |
免疫原 | KLH conjugated synthetic peptide: human G protein coupled receptor 120 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Lipid metabolism,GPCR |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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