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Anti-GRM2+GRM4 Polyclonal Antibody

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货号 TMAB-06792

Anti-GRM2+GRM4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GRM2+GRM4。Anti-GRM2+GRM4 Polyclonal Antibody 可用于 WB。

Anti-GRM2+GRM4 Polyclonal Antibody

Anti-GRM2+GRM4 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06792

Anti-GRM2+GRM4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GRM2+GRM4。Anti-GRM2+GRM4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-GRM2+GRM4 Polyclonal Antibody is a Rabbit antibody targeting GRM2+GRM4. Anti-GRM2+GRM4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Widely expressed in different regions of the adult brain as well as in fetal brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GRM2+GRM4
抗原种属
Human
基因名称
GRM2
基因ID
蛋白名称
Metabotropic glutamate receptor 2
Uniprot ID
功能
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
化学信息
分子量Theoretical: 102 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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