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IL-20RB Protein, Human, Recombinant (hFc)

IL-20RB Protein, Human, Recombinant (hFc)

产品编号 TMPJ-00194
别名: DIRS1, IL-20R-β, Interleukin-20 receptor subunit β, IL-20 receptor subunit beta, IL-20RB, interleukin-20 receptor II, hCG_2022374, fibronectin type III domain containing 6, IL-20 receptor subunit β, Interleukin-20 receptor subunit beta, MGC34923, FNDC6, IL-20R-beta, IL-20R2

Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.

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IL-20RB Protein, Human, Recombinant (hFc)
规格 价格/CNY 货期 数量
10 μg ¥ 740 5日内发货
50 μg ¥ 1,970 5日内发货
500 μg ¥ 8,860 5日内发货
1 mg ¥ 12,600 5日内发货
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产品目录号及名称: IL-20RB Protein, Human, Recombinant (hFc) (TMPJ-00194)
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产品描述 Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.
种属 Human
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 Q6UXL0
别名 DIRS1, IL-20R-β, Interleukin-20 receptor subunit β, IL-20 receptor subunit beta, IL-20RB, interleukin-20 receptor II, hCG_2022374, fibronectin type III domain containing 6, IL-20 receptor subunit β, Interleukin-20 receptor subunit beta, MGC34923, FNDC6, IL-20R-beta, IL-20R2
氨基酸序列 Asp30-Ala230
蛋白构建 Asp30-Ala230
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量 60-85 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.

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Keywords

IL-20RB Protein, Human, Recombinant (hFc) MGC-34923 DIRS1 IL-20R-β Interleukin-20 receptor subunit β IL-20 receptor subunit beta IL-20RB interleukin-20 receptor II DIRS-1 hCG_2022374 fibronectin type III domain containing 6 IL-20 receptor subunit β MGC 34923 Interleukin-20 receptor subunit beta MGC34923 FNDC-6 FNDC6 DIRS 1 IL-20R-beta FNDC 6 IL-20R2 recombinant recombinant-proteins proteins protein

 

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