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Anti-HAS2 Antibody (1J651) 是一种 Mouse 抗体,靶向 HAS2。Anti-HAS2 Antibody (1J651) 可用于 WB。
Anti-HAS2 Antibody (1J651) 是一种 Mouse 抗体,靶向 HAS2。Anti-HAS2 Antibody (1J651) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 |
| 产品描述 | Anti-HAS2 Antibody (1J651) is a Mouse antibody targeting HAS2. Anti-HAS2 Antibody (1J651) can be used in WB. |
| Ig Type | IgG1, k |
| 克隆号 | 1J651 |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expressed in fibroblasts. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS2 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to glycosaminoglycan synthetase (DG42) from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human HAS2 |
| 抗原种属 | Human |
| 基因名称 | HAS2 |
| 基因ID | |
| 蛋白名称 | Hyaluronan synthase 2 |
| Uniprot ID | |
| 功能 | Plays a role in hyaluronan/hyaluronic acid (HA) synthesis. |
| 分子量 | Theoretical: 64 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |