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Anti-HAS2 Antibody (1J651)

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货号 TMAB-06891

Anti-HAS2 Antibody (1J651) 是一种 Mouse 抗体,靶向 HAS2。Anti-HAS2 Antibody (1J651) 可用于 WB。

Anti-HAS2 Antibody (1J651)

Anti-HAS2 Antibody (1J651)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06891

Anti-HAS2 Antibody (1J651) 是一种 Mouse 抗体,靶向 HAS2。Anti-HAS2 Antibody (1J651) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍


生物活性
产品描述
Anti-HAS2 Antibody (1J651) is a Mouse antibody targeting HAS2. Anti-HAS2 Antibody (1J651) can be used in WB.
Ig Type
IgG1, k
克隆号
1J651
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Membrane.
组织特异性Expressed in fibroblasts.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS2 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to glycosaminoglycan synthetase (DG42) from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human HAS2
抗原种属
Human
基因名称
HAS2
基因ID
蛋白名称
Hyaluronan synthase 2
Uniprot ID
功能
Plays a role in hyaluronan/hyaluronic acid (HA) synthesis.
化学信息
分子量Theoretical: 64 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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