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Anti-MGEA5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MGEA5。Anti-MGEA5 Polyclonal Antibody 可用于 WB。
Anti-MGEA5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MGEA5。Anti-MGEA5 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-MGEA5 Polyclonal Antibody is a Rabbit antibody targeting MGEA5. Anti-MGEA5 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform 3: Nucleus. Isoform 1: Cytoplasm. |
| 组织特异性 | Ubiquitous. Shows highest expression in the brain, placenta and pancreas. [PTM] Proteolytically cleaved by caspase-3. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human MGEA5 |
| 抗原种属 | Human |
| 基因名称 | OGA |
| 基因ID | |
| 蛋白名称 | Protein O-GlcNAcase |
| Uniprot ID | |
| 功能 | Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3 (By similarity). |
| 分子量 | Theoretical: 103 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |