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Anti-S100P Antibody (1B730)

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产品编号 TMAY-02403
别名 S100 calcium binding protein P, MIG9

Anti-S100P Antibody (1B730) 是一种 Rabbit 抗体,靶向 S100P。Anti-S100P Antibody (1B730) 可用于 FCM。

Anti-S100P Antibody (1B730)

Anti-S100P Antibody (1B730)

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产品编号 TMAY-02403 别名 S100 calcium binding protein P, MIG9

Anti-S100P Antibody (1B730) 是一种 Rabbit 抗体,靶向 S100P。Anti-S100P Antibody (1B730) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-S100P Antibody (1B730) is a Rabbit antibody targeting S100P. Anti-S100P Antibody (1B730) can be used in FCM.
别名S100 calcium binding protein P, MIG9
Ig Type
Monoclonal Rabbit IgG
克隆号
1B730
交叉反应
Human
验证活性
Flow cytometric analysis of Human S100P expression on HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human S100P, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human S100P (rh S100P; TMPY-02216; P25815; Met1-Lys95).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Protein S100-P, also known as Protein S100-E, S100 calcium-binding protein P, S100P and S100E, is a nucleus and cytoplasm protein that belongs to the S-100 family. S100P / S100E contains twoEF-hand domains. S100P protein regulates calcium signal transduction and mediates cytoskeletal interaction, protein phosphorylation and transcriptional control. S100P / S100E overexpression can upregulate androgen receptor expression and thereby promote prostate cancer progression by increasing cell growth. S100P / S100E may directly confer resistance to chemotherapy. S100P / S100E induction may be considered an important step in the initial stage of lung adenocarcinomas, whereas its downregulation in advanced stages seems to be important for tumour progression in which DNA methylation and/or feedback transcription processes play a critical role. S100P / S100E plays a major role in the aggressiveness of pancreatic cancer that is likely mediated by its ability to activate RAGE. Interference with S100P / S100E may provide a novel approach for treatment of pancreatic cancer. S100P / S100E could be considered a potential drug target or a chemosensitization target, and could also serve as a biomarker for aggressive, hormone-refractory and metastatic prostate cancer.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human S100P Protein (TMPY-02216)
抗原种属
Human
研究领域
Calcium-binding Proteins and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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