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Anti-CD16 Antibody (7L770)

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货号 TMAB-03862

Anti-CD16 Antibody (7L770) 是一种 Rabbit 抗体,靶向 CD16。Anti-CD16 Antibody (7L770) 可用于 IHC-P,IHC-Fr,IF。

Anti-CD16 Antibody (7L770)

Anti-CD16 Antibody (7L770)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03862

Anti-CD16 Antibody (7L770) 是一种 Rabbit 抗体,靶向 CD16。Anti-CD16 Antibody (7L770) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,380
5日内发货
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产品介绍


生物活性
产品描述
Anti-CD16 Antibody (7L770) is a Rabbit antibody targeting CD16. Anti-CD16 Antibody (7L770) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
7L770
反应种属
Human,Rat
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:200-2000; IHC-Fr: 1:200-2000; IF: 1:200-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Secreted. Exists also as a soluble receptor.
组织特异性Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
抗原信息
免疫原
A synthesized peptide: human CD16
抗原种属
Human
基因名称
FCGR3A
基因ID
蛋白名称
Low affinity immunoglobulin gamma Fc region receptor III-A
Uniprot ID
功能
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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