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Anti-VPS26 Antibody (5Y706) 是一种 Rabbit 抗体,靶向 VPS26。Anti-VPS26 Antibody (5Y706) 可用于 WB,IHC,IP。
Anti-VPS26 Antibody (5Y706) 是一种 Rabbit 抗体,靶向 VPS26。Anti-VPS26 Antibody (5Y706) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-VPS26 Antibody (5Y706) is a Rabbit antibody targeting VPS26. Anti-VPS26 Antibody (5Y706) can be used in WB,IHC,IP. |
别名 | VPS26A, VPS 26A, VPS 26, VP26A_HUMAN, Vesicle protein sorting 26A, Vesicle protein sorting 26, Vacuolar protein sorting-associated protein 26A, Vacuolar protein sorting associated protein 26A, Vacuolar protein sorting 26A, Vacuolar protein sorting 26 yeast homolog, Vacuolar protein sorting 26 yeast, Vacuolar protein sorting 26 homolog A yeast, Vacuolar protein sorting 26 homolog A S. pombe, Vacuolar protein sorting 26 homolog A, Vacuolar protein sorting 26 A, Vacuolar protein sorting 26, PEP8A, PEP 8A, MGC94168, hVPS26, hVPS 26, Hbeta58 homolog, Hbeta58, Hbeta 58 homolog, Hbeta 58, HB58, HB 58, FLJ12930 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of VPS26 on different cell lysates using anti-VPS26 at 1/500 dilution. Positive control: Line 1: Rat kidney tissue, Line 2: A431. 2. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-VPS26 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-VPS26 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-VPS26 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; IP: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. Required for retrograde transport of lysosomal enzyme receptor IGF2R. Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Required for the endosomal localization of WASHC2A (indicative for the WASH complex). Required for the endosomal localization of TBC1D5. Mediates retromer cargo recognition of SORL1 and is involved in trafficking of SORL1 implicated in sorting and processing of APP. Involved in retromer-independent lysosomal sorting of F2R. Involved in recycling of ADRB2. Enhances the affinity of SNX27 for PDZ-binding motifs in cargo proteins. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 38 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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