Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Berberine ursodeoxycholate (HTD1801) 是一种口服有效的降血脂剂 ,是 Berberine 和 Ursodeoxycholic acid 的一种离子盐。Berberine ursodeoxycholate 具有广泛的代谢活性,可显著降低肝脏脂肪含量。Berberine ursodeoxycholate 可用于研究高脂血症、非酒精性脂肪性肝炎 (NASH) 和糖尿病。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 397 | 现货 | ||
5 mg | ¥ 745 | 现货 | ||
10 mg | ¥ 1,190 | 现货 | ||
25 mg | ¥ 2,380 | 现货 | ||
50 mg | ¥ 3,820 | 现货 | ||
100 mg | ¥ 5,720 | 现货 | ||
500 mg | ¥ 11,300 | 现货 |
产品描述 | Berberine ursodeoxycholate (HTD1801) is an orally effective hypolipidemic agent, an ionic salt of Berberine and Ursodeoxycholic acid.Berberine ursodeoxycholate has a wide range of metabolic activity and significantly reduces liver fat content. Berberine ursodeoxycholate has been used in studies of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes. |
体内活性 | Berberine ursodeoxycholate (BUDCA) tested in this phase 2 study (1000 mg twice a day) results in a significant reduction in liver fat content after 18 weeks of treatment. This improvement in liver fat content is associated with improvement in glycemic control, the apparent improvement in hepatic inflammation and injury with reductions in serum levels of liver associated enzymes, significant weight loss, and modest reductions in serum lipid levels.[1] |
别名 | HTD1801, BUDCA |
分子量 | 217.69 |
分子式 | C6H8CuN3O2 |
CAS No. | 1868138-66-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6.9 mg/mL (9.5 mM), Sonication and heating to 60℃ are recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 4.5937 mL | 22.9684 mL | 45.9369 mL | 114.8422 mL |
5 mM | 0.9187 mL | 4.5937 mL | 9.1874 mL | 22.9684 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Berberine ursodeoxycholate 1868138-66-2 HTD1801 HTD-1801 BUDCA HTD 1801 Inhibitor inhibitor inhibit