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顶部生物活性储存和溶解信息计算器

Anti-SIRP gamma Antibody (2L641)

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产品编号 TMAY-02076

别名 SIRP γ/SIRPG, signal-regulatory protein γ, signal-regulatory protein gamma

Anti-SIRP gamma Antibody (2L641) 是一种 Mouse 抗体，靶向 SIRP gamma。Anti-SIRP gamma Antibody (2L641) 可用于 ELISA。

Anti-SIRP gamma Antibody (2L641)

Anti-SIRP gamma Antibody (2L641)

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Rating icon 还可以
产品编号 TMAY-02076 别名 SIRP γ/SIRPG, signal-regulatory protein γ, signal-regulatory protein gamma

Anti-SIRP gamma Antibody (2L641) 是一种 Mouse 抗体，靶向 SIRP gamma。Anti-SIRP gamma Antibody (2L641) 可用于 ELISA。

规格价格库存数量
20 μL
¥ 590
5日内发货
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-SIRP gamma Antibody (2L641) is a Mouse antibody targeting SIRP gamma. Anti-SIRP gamma Antibody (2L641) can be used in ELISA.
别名SIRP γ/SIRPG, signal-regulatory protein γ, signal-regulatory protein gamma
Ig Type
Mouse IgG1
克隆号
2L641
交叉反应
Human
特异性
Human SIRP gamma/SIRPG
No cross-reactivity in ELISA with
Human cell lysate (293 cell line)
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SIRPG / SIRP gamma / CD172g (rh SIRPG / SIRP gamma / CD172g; TMPY-01853; NP_061026.2; Met 1-Ser 364). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPG/SIRP gamma/CD172g is a probable immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG can mediate cell-cell adhesion. SIRPG/SIRP gamma is engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG/SIRP gamma/CD172g is detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. This cytokine is mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, SIRPG is primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human SIRPG / SIRP gamma / CD172g protein (TMPY-01853)
抗原种属
Human
研究领域
Phosphatases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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