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Anti-Carbonic Anhydrase 12 Antibody (7S411)
还可以产品编号 TMAY-01033
Anti-Carbonic Anhydrase 12 Antibody (7S411) 是一种 Mouse 抗体，靶向 Carbonic Anhydrase 12。Anti-Carbonic Anhydrase 12 Antibody (7S411) 可用于 FCM。
Anti-Carbonic Anhydrase 12 Antibody (7S411)
Anti-Carbonic Anhydrase 12 Antibody (7S411)
还可以产品编号 TMAY-01033
Anti-Carbonic Anhydrase 12 Antibody (7S411) 是一种 Mouse 抗体，靶向 Carbonic Anhydrase 12。Anti-Carbonic Anhydrase 12 Antibody (7S411) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Carbonic Anhydrase 12 Antibody (7S411) is a Mouse antibody targeting Carbonic Anhydrase 12. Anti-Carbonic Anhydrase 12 Antibody (7S411) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7S411 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CA12 expression on MCF-7 cells. Cells were stained with purified anti-Human CA12, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carbonic Anhydrase XII (rh Carbonic Anhydrase XII; TMPY-00694; NP_001209.1; Met1-Gln291). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker. rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | FITC/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human Carbonic Anhydrase XII protein (TMPY-00694) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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