购物车
- 全部删除
您的购物车当前为空
- 1040个与DNA损伤和修复紧密相关的化合物集合，是高通量筛选，高内涵筛选的良好载体；
- 涵盖与DNA损伤和修复相关的热门靶点，如HDAC、DNA/RNA Synthesis、Topoisomerase等；
- 通过临床前研究和临床实验，生物活性和生物安全性得到保障；
- 结构多样，药效显著，可渗透细胞；
- 详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
DNA 损伤和修复分子库
DNA Damage & Repair Compound Library
很棒癌细胞的耐药性是癌症治疗过程中面临的主要挑战，因此鉴定新的生物学靶标，并开发设计相应的药物成为重要策略，在各种潜在候选靶标中，癌细胞 DNA Damage & Repair 系统是重要的靶标。由于抗生素的滥用，细菌等微生物的耐药性越来越强，开发靶向微生物 DNA Damage & Repair 系统的药物迫在眉睫。 TargetMol DNA 损伤和修复分子库是1040 个与DNA 损伤和修复紧密相关的化合物集合，可用于DNA 损伤和修复相关研究的高通量筛选，高内涵筛选。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
资源下载
化合物库相关信息
Excel
SDF
联系我们获取更多批次信息产品编号 L3900
DNA 损伤和修复分子库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
SCI 文献
化合物库定制
您可以通过点击按钮
定制您专属的化合物！
联系专属定制定制您专属的化合物！
文献引用
1.Tian D, Tang J, Geng X, et al Targeting UHRF1-dependent DNA repair selectively sensitizes KRAS mutant lung cancer to chemotherapy. Cancer Letters. 20202.Khalid U, Simovic M, Iskar M, et al. A synergistic interaction between HDAC-and PARP inhibitors in childhood tumors with chromothripsis. International Journal of Cancer. 2022 Aug 15;151(4):590-606. doi: 10.1002/ijc.34027. Epub 2022 Apr 28.3.Khalid U, Simovic M, Hammann L A, et al. A synergistic interaction between HDAC‐and PARP inhibitors in childhood tumors with chromothripsis. International Journal of Cancer. 2022
化合物库组成
DNA/RNA Synthesis
Apoptosis
PPAR
HDAC
Topoisomerase
Autophagy
PARP
Nucleoside Antimetabolite/Analog
Antibacterial
Antibiotic
Sirtuin
Endogenous Metabolite
DUB
DNA-PK
PI3K
ATM/ATR
DNA
DNA Alkylator/Crosslinker
DHFR
DNA Alkylation
Influenza Virus
HIV Protease
mTOR
NF-κB
Parasite
HSV
Dehydrogenase
Telomerase
Caspase
COX
DNA gyrase
Wnt/beta-catenin
Mitophagy
Antifungal
Bcl-2 Family
SARS-CoV
Virus Protease
Antifolate
p53
Reactive Oxygen Species
ADC Cytotoxin
Ferroptosis
p38 MAPK
Potassium Channel
AMPK
HCV Protease
Lipoxygenase
Akt
CRISPR/Cas9
Cytochromes P450
Epigenetic Reader Domain
GABA Receptor
PDE
Antiviral
BMI-1
CDK
DNA Methyltransferase
HBV
PKC
Reverse Transcriptase
Tyrosinase
Antifection
Bcr-Abl
IL Receptor
MicroRNA
MTH1
Nrf2
Prostaglandin Receptor
STAT
TGF-beta/Smad
TNF
TRP/TRPV Channel
ABC Transporter
AChR
Adenosine Receptor
Antioxidant
Calcium Channel
Cannabinoid Receptor
Carbonic Anhydrase
Drug Metabolite
EGFR
FLT
Gamma-secretase
GPR
HSP
LDL
Microtubule Associated
Mitochondrial Metabolism
MMP
NO Synthase
PKA
Sodium Channel
transporter
Adrenergic Receptor
Arginase
ATPase
Carboxypeptidase
Casein Kinase
cGAS
c-Met/HGFR
Cysteine Protease
ERK
Free radical scavengers
HIF/HIF Prolyl-Hydroxylase
Histone Acetyltransferase
IAP
Immunology/Inflammation related
Interleukin
IκB/IKK
JAK
JNK
Mdm2
MEK
PAK
P-gp
Phosphatase
Phospholipase
PI4K
Proteasome
RAAS
Retinoid Receptor
Syk
Thrombin
Transferase
Tyrosine Kinases
VEGFR
5-HT Receptor
Aminopeptidase
Androgen Receptor
Anti-infection
Aromatase
Aurora Kinase
CCR
c-Fms
c-Kit
c-Myc
c-RET
Dopamine Receptor
E1/E2/E3 Enzyme
Epoxide Hydrolase
Estrogen/progestogen Receptor
FAK
Fatty Acid Synthase
FLAP
Glucokinase
Glutathione Peroxidase
Hedgehog/Smoothened
HER
Histamine Receptor
Histone Demethylase
IDO
IGF-1R
Integrin
KLF
Leukotriene Receptor
LRRK2
MAO
MAPK
MLK
Monoamine Oxidase
NADPH
NMDAR
NOD
NOD-like Receptor (NLR)
OCT
P2X Receptor
P2Y Receptor
PAFR
PDGFR
PLK
Proton pump
ribosome
ROCK
ROS
RSV
Serine/threonin kinase
SGK
Src
TAM Receptor
TLR
Trk receptor
化合物库信息
| Empty | 99873-43-5 | 99-66-1 | 99009-20-8 | 98079-52-8 | 98079-51-7 | 97919-22-7 | 97682-44-5 | 97540-22-2 | 97322-87-7 | 96187-53-0 | Empty |
| Droxinostat | Valproic Acid | Pyrazoloacridine | Lomefloxacin hydrochloride | Lomefloxacin | Chloroquinoxaline sulfonamide | Irinotecan | S-Adenosyl-L-methionine disulfate tosylate | Troglitazone | Brequinar | ||
| Empty | 96017-59-3 | 959-23-9 | 95853-92-2 | 957-77-7 | 956958-53-5 | 955977-50-1 | 955900-27-3 | 951-78-0 | 950762-95-5 | 95058-81-4 | Empty |
| 2-hexyl-4-Pentynoic Acid | 4'-Methoxychalcone | CGS 15435 | 5-Hydroxyuridine | Pilaralisib analogue | PI-3065 | RK-9123016 | 2'-Deoxyuridine | PCI-34051 | Gemcitabine | ||
| Empty | 950225-08-8 | 949898-66-2 | 94987-08-3 | 948-60-7 | 94-75-7 | 946150-57-8 | 945619-74-9 | 945152-88-5 | 943119-42-4 | 93919-41-6 | Empty |
| TTP-8307 | AS-136A | Gypenoside XLIX | Pterine-6-carboxylic acid | 2,4-D | Remetinostat | OPHIOPOGONIN D | Antiviral agent 34 | OUL232 | Deoxyguanosine triphosphate trisodium salt | ||
| Empty | 937039-45-7 | 936890-98-1 | 935881-37-1 | 934828-12-3 | 934493-76-2 | 934162-61-5 | 932-53-6 | 93183-15-4 | 93117-08-9 | 93106-60-6 | Empty |
| Pimelic diphenylamide 106 | OSI-027 | AR42 | CXD101 | Voxtalisib | A-966492 | 6-AZATHYMINE | DMT-dG(ib) Phosphoramidite | 5-AIQ | Enrofloxacin | ||
| Empty | 929016-96-6 | 928659-17-0 | 92831-11-3 | 927961-18-0 | 926908-04-5 | 926259-99-6 | 925701-49-1 | 925434-55-5 | 925432-73-1 | 924296-19-5 | Empty |
| Pracinostat | Triazavirin | MN-64 | Lanifibranor | HNHA | BG45 | KU60019 | SRT 1720 | SRT 1460 | DUB-IN-2 | ||
| Empty | 924296-18-4 | 924296-17-3 | 923978-27-2 | 92285-87-5 | 919091-63-7 | 91653-50-8 | 915360-05-3 | 915303-09-2 | 915019-65-7 | 914382-60-8 | Empty |
| DUB-IN-1 | DUB-IN-3 | Elafibranor | L82-G17 | RA-9 | Zingiberen newsaponin | IndiMitecan | Indotecan | Dactolisib | Tefinostat | ||
| Empty | 91432-48-3 | 91421-43-1 | 91421-42-0 | 912445-05-7 | 912444-00-9 | 910462-43-0 | 90906-40-4 | 905973-89-9 | 90417-38-2 | 902128-92-1 | Empty |
| Ascamycin | 9-amino-CPT | Rubitecan | Veliparib dihydrochloride | Veliparib | Domatinostat | (±)4-HDHA | CGK733 | NU1025 | E7016 | ||
| Empty | 896705-16-1 | 89-57-6 | 89412-79-3 | 892128-60-8 | 891002-11-2 | 888478-45-3 | 887686-02-4 | 882257-11-6 | 882-09-7 | 881375-00-4 | Empty |
| BMH-21 | 5-Aminosalicylic Acid | Raddeanin A | LY2334737 | SIRT6-IN-5 | Supinoxin | OSS_128167 | P005091 | Clofibric acid | KU-0060648 |
嗨！有任何问题？点我咨询
