Phenoxyethanol

Name: Phenoxyethanol
Brand: TargetMol
SKU: T20293
Price: 195 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.47%

货号 T20293Cas号 122-99-6

别名 乙二醇苯醚, NSC-1864, NSC1864, NSC 1864

Phenoxyethanol (NSC-1864) 是广谱抗菌剂，被用作化妆品、疫苗和纺织品中的防腐剂。它是呼吸作用氧化磷酸化的解偶联剂，竞争性地抑制苹果酸脱氢酶。

Phenoxyethanol

一键复制产品信息

很棒

纯度: 99.47%

货号 T20293 别名 乙二醇苯醚, NSC-1864, NSC1864, NSC 1864Cas号 122-99-6

Phenoxyethanol (NSC-1864) 是广谱抗菌剂，被用作化妆品、疫苗和纺织品中的防腐剂。它是呼吸作用氧化磷酸化的解偶联剂，竞争性地抑制苹果酸脱氢酶。

规格	价格	库存
100 mg	¥ 196	现货
1 g	¥ 495	现货
1 mL x 10 mM (in DMSO)	¥ 195	现货

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纯度: 99.47%

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COA LCMS HNMR 产品操作手册

产品介绍

Phenoxyethanol AI Summary

Phenoxyethanol exhibits a diverse range of bioactivities. It acts as an inhibitor of RecQ-Like DNA Helicase 1 and Aldehyde Dehydrogenase 1 with potencies of 12589.3 nM and 39810.7 nM, respectively. Additionally, it functions as an agonist for retinoid X receptor alpha, androgen receptor, and thyroid hormone receptor beta signaling, showing potencies from 15848.9 nM to 4.0 nM. It also antagonizes androgen receptor and glucocorticoid receptor signaling with potencies of 1000000.0 nM and 0.7 nM respectively. The compound affects cell viability in LYMP2-005 and S16 Schwann cell assays with potencies of 3162.3 nM and 80.9 nM. It activates several pathways, including p53, rat pregnane X receptor, and the fibrous dysplasia/McCune-Albright syndrome pathway, with potencies from 56234.1 nM to 8912.5 nM, and inhibits Polymerase Iota at 79432.8 nM. In antiviral assays, it blocks Ebola Virus entry with AC50 values ranging from 562.3 nM to 7.943 µM. Furthermore, Phenoxyethanol shows antibacterial activity against Staphylococcus aureus MN8, more effectively reducing bacterial activity and inhibiting toxin TSST-1 production at a 0.10% concentration compared to 0.50% after 24 hours..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.
别名	乙二醇苯醚, NSC-1864, NSC1864, NSC 1864

化学信息

分子量	138.16
分子式	C₈H₁₀O₂
CAS No.	122-99-6
Smiles	OCCOC1=CC=CC=C1
密度	1.11. Temperature:20 °C.
颜色	Transparent
物理性状	Liquid

储存&溶解度

存储

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 55 mg/mL (398.09 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (14.48 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.2380 mL	36.1899 mL	72.3798 mL	361.8992 mL
5 mM	1.4476 mL	7.2380 mL	14.4760 mL	72.3798 mL
10 mM	0.7238 mL	3.6190 mL	7.2380 mL	36.1899 mL
20 mM	0.3619 mL	1.8095 mL	3.6190 mL	18.0950 mL
50 mM	0.1448 mL	0.7238 mL	1.4476 mL	7.2380 mL
100 mM	0.0724 mL	0.3619 mL	0.7238 mL	3.6190 mL