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Anti-EIF2C Polyclonal Antibody

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货号 TMAB-05495

Anti-EIF2C Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EIF2C。Anti-EIF2C Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-EIF2C Polyclonal Antibody

Anti-EIF2C Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05495

Anti-EIF2C Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EIF2C。Anti-EIF2C Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-EIF2C Polyclonal Antibody is a Rabbit antibody targeting EIF2C. Anti-EIF2C Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Horse,Fruit Fly)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, P-body.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ago1 belongs to the argonaute family and contains 1 PAZ and 1 Piwi domain. It is required for G1 arrest and mating in response to nitrogen starvation. It is also known as cell cycle control protein through it's regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. It is required, indirectly, for regulated hyperphosphorylation of cdc2. Ago 1 also has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. It has been shown to be non-essential for siRNA-directed target RNA cleavage but is needed for the production of mature miRNA that affects miRNA-directed RNA cleavage.
抗原信息
免疫原
KLH conjugated synthetic peptide: human EIF2C1/Ago1
抗原种属
Human
基因名称
AGO1
基因ID
蛋白名称
Protein argonaute-1
Uniprot ID
功能
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
化学信息
分子量Theoretical: 94 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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