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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-AGT Monoclonal Antibody

Synonyms: Serpin A8, Angiotensinogen
货号 TMAZ-0159 一键复制产品信息
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Anti-AGT Monoclonal Antibody 是一种人源化 rabbit 抗体，靶向 AGT。Anti-AGT Monoclonal Antibody 可用于 ELISA, FCM。

Anti-AGT Monoclonal Antibody

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货号 TMAZ-0159

别名 Serpin A8, Angiotensinogen

Anti-AGT Monoclonal Antibody 是一种人源化 rabbit 抗体，靶向 AGT。Anti-AGT Monoclonal Antibody 可用于 ELISA, FCM。

Anti-AGT Monoclonal Antibody
规格价格库存数量
25 μg
¥ 1,250
7日内发货
50 μg
¥ 1,500
7日内发货
100 μg
¥ 2,099
7日内发货
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产品介绍

生物活性
产品描述
Anti-AGT Monoclonal Antibody 是一种 humanized rabbit antibody targeting AGT. Anti-AGT Monoclonal Antibody can be used in FCM.
别名
Serpin A8, Angiotensinogen
Ig Type
Rabbit monoclonal IgG
反应种属
Human
验证活性
Flow cytometry analysis of AGT overexpressed 435F cells with TMAZ-0159, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用FCM
推荐剂量
0.1-0.2 μg/10^6 cells for FCM
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of AGT protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis|Acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone (PubMed: 10619573, PubMed: 17138938). Acts by binding to angiotensin receptors AGTR1 and AGTR2 (PubMed: 1567413). Also binds the DEAR/FBXW7-AS1 receptor (By similarity)|Stimulates aldosterone release|Is a ligand for the G-protein coupled receptor MAS1 (By similarity). Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets (By similarity)
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin
可提供抗体种类
2
抗原信息
免疫原
AGT
抗原种属
Human
基因ID
183
Uniprot ID
P01019
研究领域
Drug Target
化学信息
分子量150 kDa
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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