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Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 2
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产品编号 TMAC-00198
别名 p-Androgen receptor (Y363), p-Androgen receptor (Tyr363), Androgen receptor (p-Y363), Androgen receptor (p-Tyr363)
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Androgen receptor (Tyr363)。Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 可用于 WB。
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 2
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 2
还可以产品编号 TMAC-00198 别名 p-Androgen receptor (Y363), p-Androgen receptor (Tyr363), Androgen receptor (p-Y363), Androgen receptor (p-Tyr363)
Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Androgen receptor (Tyr363)。Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,245 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Androgen receptor (Tyr363). Anti-Phospho-Androgen receptor (Tyr363) Polyclonal Antibody can be used in WB. |
| 别名 | p-Androgen receptor (Y363), p-Androgen receptor (Tyr363), Androgen receptor (p-Y363), Androgen receptor (p-Tyr363) |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Western blot analysis of extracts from HuvEc cells (Lane 2), COS7 cells (Lane 3) and JK cells (Lane 4), using Androgen Receptor (Phospho-Tyr363) Antibody TMAC-00198. The lane on the left is treated with antigen-specific peptide. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 性状 | Liquid |
| 缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | Peptide sequence around phosphorylation site of tyrosine 363 (D-Y-Y(p)-N-F) derived from Human Androgen Receptor |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Actual: 85 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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