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Anti-GRIA2 Antibody (7M320) 是一种抗体,靶向 GRIA2。Anti-GRIA2 Antibody (7M320) 可用于 ELISA。
Anti-GRIA2 Antibody (7M320) 是一种抗体,靶向 GRIA2。Anti-GRIA2 Antibody (7M320) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,310 | 5日内发货 | |
100 μL | ¥ 2,195 | 5日内发货 |
产品描述 | Anti-GRIA2 Antibody (7M320) is an antibody targeting GRIA2. Anti-GRIA2 Antibody (7M320) can be used in ELISA. |
Ig Type | Rabbit IgG |
克隆号 | 7M320 |
交叉反应 | Human |
应用 | ELISA |
抗体种类 | Monoclonal |
亚细胞定位 | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density membrane; Multi-pass membrane protein. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system. It plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Through complex formation with NSG1, GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human GRIA2 |
抗原种属 | Human |
基因ID | 2891 |
Uniprot ID | |
研究领域 | Neuroscience |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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