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Anti-GRIA2 Antibody (7M320)

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产品编号 TMAH-00513

Anti-GRIA2 Antibody (7M320) 是一种抗体,靶向 GRIA2。Anti-GRIA2 Antibody (7M320) 可用于 ELISA。

Anti-GRIA2 Antibody (7M320)

Anti-GRIA2 Antibody (7M320)

Rating icon 还可以
产品编号 TMAH-00513

Anti-GRIA2 Antibody (7M320) 是一种抗体,靶向 GRIA2。Anti-GRIA2 Antibody (7M320) 可用于 ELISA。

规格价格库存数量
50 μL
¥ 1,310
5日内发货
100 μL
¥ 2,195
5日内发货
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产品介绍

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产品描述
Anti-GRIA2 Antibody (7M320) is an antibody targeting GRIA2. Anti-GRIA2 Antibody (7M320) can be used in ELISA.
Ig Type
Rabbit IgG
克隆号
7M320
交叉反应
Human
应用
ELISA
抗体种类
Monoclonal
亚细胞定位Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density membrane; Multi-pass membrane protein.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system. It plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Through complex formation with NSG1, GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human GRIA2
抗原种属
Human
基因ID
2891
Uniprot ID
研究领域
Neuroscience
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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