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Anti-VEGF165 Polyclonal Antibody
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产品编号 TMAB-01947
别名 VPF, VEGFA, VEGF, Vascular permeability factor, L-VEGF
Anti-VEGF165 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 VEGF165。Anti-VEGF165 Polyclonal Antibody 可用于 WB,ELISA。
Anti-VEGF165 Polyclonal Antibody
Anti-VEGF165 Polyclonal Antibody
还可以产品编号 TMAB-01947 别名 VPF, VEGFA, VEGF, Vascular permeability factor, L-VEGF
Anti-VEGF165 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 VEGF165。Anti-VEGF165 Polyclonal Antibody 可用于 WB,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 |
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产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-VEGF165 Polyclonal Antibody is a Rabbit antibody targeting VEGF165. Anti-VEGF165 Polyclonal Antibody can be used in WB,ELISA. |
| 疾病造模方案 | |
| 别名 | VPF, VEGFA, VEGF, Vascular permeability factor, L-VEGF |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 25 μg total protein per Lane of various lysates probed with VEGF165 polyclonal antibody, unconjugated (TMAB-01947) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted. Note=VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding properties and, although a signicant proportion remains cell-associated, most is freely secreted. VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin. |
| 组织特异性 | soform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels. To be specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature). |
| 免疫原 | Recombinant Protein: human VEGF165 Protein |
| 抗原种属 | Human |
| 基因名称 | VEGFA |
| 基因ID | |
| 蛋白名称 | Vascular endothelial growth factor A |
| Uniprot ID | |
| 研究领域 | VEGF,SARS Coronavirus,Cancer,Hypoxia,Co-factors,Angiogenesis and vasculogenesis,VEGF,Angiogenic growth factors,VEGF,Response to hypoxia |
| 功能 | Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. |
| 分子量 | Theoretical: 22 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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