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Anti-MAP4K4 Antibody (7A976)

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货号 TMAB-08581

Anti-MAP4K4 Antibody (7A976) 是一种 Rabbit 抗体，靶向 MAP4K4。Anti-MAP4K4 Antibody (7A976) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-MAP4K4 Antibody (7A976)

Anti-MAP4K4 Antibody (7A976)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08581

Anti-MAP4K4 Antibody (7A976) 是一种 Rabbit 抗体，靶向 MAP4K4。Anti-MAP4K4 Antibody (7A976) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAP4K4 Antibody (7A976) is a Rabbit antibody targeting MAP4K4. Anti-MAP4K4 Antibody (7A976) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
7A976
反应种属
Human
应用IHC-PIHC-FrICC/IFIF
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human MAP4K4
抗原种属
Human
基因名称
MAP4K4
基因ID
9448
蛋白名称
Mitogen-activated protein kinase kinase kinase kinase 4
Uniprot ID
O95819
功能
Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
化学信息
分子量Theoretical: 142 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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