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Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody

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Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody
产品编号 TMAC-00449
别名 p-BLNK (Y96), p-BLNK (Tyr96), BLNK (p-Y96), BLNK (p-Tyr96)

Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-BLNK (Tyr96)。Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody 可用于 WB。

Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody

Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody
产品编号 TMAC-00449 别名 p-BLNK (Y96), p-BLNK (Tyr96), BLNK (p-Y96), BLNK (p-Tyr96)

Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-BLNK (Tyr96)。Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,235
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLNK (Tyr96). Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody can be used in WB.
别名p-BLNK (Y96), p-BLNK (Tyr96), BLNK (p-Y96), BLNK (p-Tyr96)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extracts from COLO205 tissue using BLNK (Phospho-Tyr96) antibody TMAC-00449. The lane on the right is treated with the antigen-specific peptide.
应用
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 96(D-S-Y(p)-E-P) derived from Human BLNK
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 50 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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