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Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-BLNK (Tyr96)。Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody 可用于 WB。
Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-BLNK (Tyr96)。Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLNK (Tyr96). Anti-Phospho-BLNK (Tyr96) Polyclonal Antibody can be used in WB. |
别名 | p-BLNK (Y96), p-BLNK (Tyr96), BLNK (p-Y96), BLNK (p-Tyr96) |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of extracts from COLO205 tissue using BLNK (Phospho-Tyr96) antibody TMAC-00449. The lane on the right is treated with the antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 96(D-S-Y(p)-E-P) derived from Human BLNK |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 50 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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