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Anti-IGFBP-6 Antibody (8T13)
还可以产品编号 TMAY-02436
Anti-IGFBP-6 Antibody (8T13) 是一种 Mouse 抗体，靶向 IGFBP-6。Anti-IGFBP-6 Antibody (8T13) 可用于 ELISA(Cap)。
Anti-IGFBP-6 Antibody (8T13)
Anti-IGFBP-6 Antibody (8T13)
还可以产品编号 TMAY-02436
Anti-IGFBP-6 Antibody (8T13) 是一种 Mouse 抗体，靶向 IGFBP-6。Anti-IGFBP-6 Antibody (8T13) 可用于 ELISA(Cap)。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-IGFBP-6 Antibody (8T13) is a Mouse antibody targeting IGFBP-6. Anti-IGFBP-6 Antibody (8T13) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8T13 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IGFBP6 / IBP6 (rh IGFBP6 / IBP6; TMPY-02119; P24592; Met1-Gly240). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
| 研究背景 | Insulin-like growth factor-binding protein 6 (IGFBP6) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGF-binding protein-4 (IGFBP-4) inhibits IGF-I action in vitro and is the most abundant IGFBP in the rodent arterial wall. IGFBP6 is directly downregulated by the beta-catenin/TCF complex in desmoid tumors, and imply a role for the IGF axis in the proliferation of desmoid tumors. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IGFBP6 / IBP6 Protein (TMPY-02119) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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