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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Leptin Receptor Antibody (1S966)

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货号 TMAB-08281

Anti-Leptin Receptor Antibody (1S966) 是一种 Rabbit 抗体，靶向 Leptin Receptor。Anti-Leptin Receptor Antibody (1S966) 可用于 IHC-P,IHC-Fr,IF,WB。

Anti-Leptin Receptor Antibody (1S966)

Anti-Leptin Receptor Antibody (1S966)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08281

Anti-Leptin Receptor Antibody (1S966) 是一种 Rabbit 抗体，靶向 Leptin Receptor。Anti-Leptin Receptor Antibody (1S966) 可用于 IHC-P,IHC-Fr,IF,WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

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产品描述
Anti-Leptin Receptor Antibody (1S966) is a Rabbit antibody targeting Leptin Receptor. Anti-Leptin Receptor Antibody (1S966) can be used in IHC-P,IHC-Fr,IF,WB.
Ig Type
IgG
克隆号
1S966
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIFWB
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Isoform E: Secreted (Probable). Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
组织特异性Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
抗原信息
免疫原
A synthesized peptide: human Leptin receptor
抗原种属
Human
基因名称
LEPR
基因ID
3953
蛋白名称
Leptin receptor
Uniprot ID
P48357
功能
Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
化学信息
分子量Theoretical: 126 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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