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Anti-PD-L2 Antibody-FITC (3W144)
还可以产品编号 TMAY-00569F
Anti-PD-L2 Antibody-FITC (3W144) 是一种 FITC-conjugated Rabbit 抗体，靶向 PD-L2。Anti-PD-L2 Antibody-FITC (3W144) 可用于 FCM。
Anti-PD-L2 Antibody-FITC (3W144)
Anti-PD-L2 Antibody-FITC (3W144)
还可以产品编号 TMAY-00569F
Anti-PD-L2 Antibody-FITC (3W144) 是一种 FITC-conjugated Rabbit 抗体，靶向 PD-L2。Anti-PD-L2 Antibody-FITC (3W144) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-PD-L2 Antibody-FITC (3W144) is a FITC-conjugated Rabbit antibody targeting PD-L2. Anti-PD-L2 Antibody-FITC (3W144) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3W144 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human PDL2(CD273) expression on monocyte-derived dendritic cells. Cells were stained with FITC-conjugated anti-Human PDL2(CD273). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human B7-DC / PD-L2 / CD273 / PDCD1LG2 (rh B7-DC / PD-L2 / CD273 / PDCD1LG2; TMPY-04346; NP_079515.2; Met1-Pro219) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B cells, INF-γ in monocytes, or LPS plus IFN-γ in dendritic cells. The CD28 and B7 protein families are critical regulators of immune responses. PD-L2 and PD-L1 are two ligands for PD-1, member of the CD28/CTLA4 family expressed on activated lymphoid cells, and thus provide signals for regulating T cell activation and immune tolerance. The interaction of B7-DC/PD-1 exhibited a 2-6-fold higher affinity compared with the interaction of B7-H1/PD-1.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human B7-DC / PD-L2 / CD273 / PDCD1LG2 Protein (TMPY-04346) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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